The Forbidden Sanctum

The Forbidden Sanctum is an area found in the Sanctum league. Players must explore a randomized dungeon, collecting Aureus coins and trying to reach the end before their Resolve runs out.

A Sanctum run contains 4 floors, each containing 8 rooms. The 8th room of each floor always contains a Boss. Players can choose to engage in a room every time they encounter the portal to the Sanctum in an area or map, or defer up to 8 rooms (1 floor) to be run consecutively at a later time.^[1]^[2] Crashing during a Sanctum room will reset progress for that room and will resume the same area on your next map. Aureus and rewards are only locked in upon successful completion of a room^[2]. Each Sanctum run is independent between characters on the same account.^[2]

Mechanics

Resolve

Resolve is an additional stat player characters have while exploring the Sanctum, somewhat similar to Ruin from Ultimatum league.
The default maximum Resolve is 300. Resolve is maintained between rooms, and the player is ejected from the Sanctum if it hits 0, resetting all floors and rooms. Being ejected does not count as a death, nor does it remove experience.
Resolve is lost from hits from monsters or traps in the Sanctum. Closer proximity to monsters reduces the Resolve lost on hit.^[2]
Regular defences such as evasion rating, damage reduction, and avoidance do not affect the loss of Resolve.
Minions and non-party allies do not cause Resolve to be lost if hit.
A fixed amount of Resolve can be restored in Fountain rooms.
Gaining additional Maximum Resolve will also cause the character to gain current Resolve of the same amount. Losing Maximum Resolve will not further affect the current Resolve.
Accursed Pacts that cause you to Lose #% Maximum Resolve and the Minor Affliction "Spiked Exit" can be safely taken even with only 1 Maximum Resolve, and will have no effect (they cannot fail a run by itself).
Maximum Resolve is soft capped at 1000; however, it is possible to exceed these values from sources that modify maximum Resolve at the start of a room/floor.

Aureus

Aureus is a type of non-tradeable currency similar to Azurite which can be found in the Sanctum. Aureus is collected automatically when the player is near it.
Aureus can be traded to the merchant for various Boons or Templar Relics and Sanctified Relics.
Aureus is maintained between rooms and floors, and is reset when the Sanctum run ends.
Aureus drops from Templar Stash chests, as well as from Guards and Bosses when killed.

Inspiration

Inspiration acts as a buffer over your maximum Resolve, somewhat similar to Energy Shield in comparison to life.
Inspiration cannot be recovered like Resolve.
Inspiration is soft capped at 1000; however, it is possible to exceed these values from sources that modify Inspiration at the start of a room/floor.

Boon

Above your inspiration bar, major boons are grouped in a symbol with a very thick and bright yellow bordered boon symbol, while all minor boons are grouped in a plain yellow bordered boon symbol. Boons are shown when hovering the according symbol.
Boons grant various benefits to your Sanctum run and can help recover or mitigate damage to your Resolve, increase your Aureus and rewards, debuff monsters, grant Inspiration, or provide other helpful buffs.

Boon Type	Boon Name	Description
Major Boons	All-Seeing Eye	The Sanctum Map is fully revealed ^{editor's note: overrides all afflictions and modifiers that hide parts of the Sanctum map, including The Night LampThe Night Lamp Urn RelicRequires Level 64The Herald of the Scourge drops 2 additional Sanctified Relics Rooms are unknown on the Sanctum Map This item is destroyed when your Sanctum endsUnmodifiable"The new comers were terrified of fire. He used their fear to control them, to lay the seeds of unquestioning faith. He claimed only his god could protect them." - Lycia, the HereticPlace this item on the Relic Altar at the start of each Sanctum runAccount-bound}
Major Boons	Bronze Coin	Picking up Aureus coins recovers Resolve ^{editor's note: recovers the same amount of Resolve as Aureus obtained; scaled by modifiers to Resolve recovery}
Major Boons	Bronze Descry	Ignore Resolve lost for 1 second after losing Resolve from a Hit
Major Boons	Crystal Chalice	You cannot receive any more Minor Afflictions ^{editor's note: Crystal Shard's Affliction to Boon transformation can still occur with this Boon}
Major Boons	Crystal Shard	The next Affliction you gain is converted into a random Minor Boon ^{editor's note: This Boon's Affliction to Boon transformation can still occur with Crystal Chalice}
Major Boons	Gold Coin	Aureus coins found are doubled
Major Boons	Golden Descry	Recover +15 Resolve on room completion
Major Boons	Holy Descry	Upon reaching 0 Resolve, revive with full Resolve, lose 50% of your current Maximum Resolve, and remove a random Boon ^{editor's note: this is the only Boon that can save a run with "Cannot Recover Resolve" or "Maximum Resolve is 1" modifiers, as long as the player has Boons to remove}
Major Boons	Holy Water	Gain a random Minor Boon when you use a Fountain
Major Boons	Imperial Seal	Traps are Disabled
Major Boons	Musty Wine	At the start of each room, a random Shrine effect is applied to you
Major Boons	Priest's Descry	Upon reaching 0 Resolve, revive with 75% of Maximum Resolve once ^{editor's note: does not work on no-hit runs}
Major Boons	Sacred Mirror	Duplicate up to 3 random Offer Rewards ^{editor's note: only applies to rewards deferred to end of Floor/Sanctum; can apply to same reward more than once; applies immediately once obtained to your current rewards}
Major Boons	Silver Coin	Gain 20 Aureus coins when you lose Resolve from a Hit
Major Boons	Silver Descry	Ignore the first Resolve lost from Hits in each room
Minor Boons	Adrenaline Vial	Recover 50% of your Maximum Resolve on entering Boss Room
Minor Boons	Arcane Aegis	Trigger Arcane Buffer when your Inspiration reaches 0
Minor Boons	Assassin's Blade	The next 10 Guards you Hit are killed Instantly
Minor Boons	Assassin's Blade	The next 9 Guards you Hit are killed Instantly
Minor Boons	Assassin's Blade	The next 8 Guards you Hit are killed Instantly
Minor Boons	Assassin's Blade	The next 7 Guards you Hit are killed Instantly
Minor Boons	Assassin's Blade	The next 6 Guards you Hit are killed Instantly
Minor Boons	Assassin's Blade	The next 5 Guards you Hit are killed Instantly
Minor Boons	Assassin's Blade	The next 4 Guards you Hit are killed Instantly
Minor Boons	Assassin's Blade	The next 3 Guards you Hit are killed Instantly
Minor Boons	Assassin's Blade	The next 2 Guards you Hit are killed Instantly
Minor Boons	Assassin's Blade	The next Guard you Hit is killed Instantly
Minor Boons	Black Pearl	Traps impact 50% reduced Resolve ^{editor's note: affects both Resolve and Inspiration loss}
Minor Boons	Chipped Dice	The Merchant's Shop can be Rerolled
Minor Boons	Divinia's Gift	Your next purchase from the Merchant has no cost
Minor Boons	Enchanted Urn	30% increased Effect of your non-Unique Relics
Minor Boons	Engraved Orb	100% increased Resolve recovered while Resolve is below 50%
Minor Boons	Fountain of Youth	Gain +40 Maximum Resolve each time you use a Fountain
Minor Boons	Fright Mask	Monsters deal 40% less Damage
Minor Boons	Gilded Lyre	Gain +250 Inspiration at the start of each floor
Minor Boons	Glowing Orb	The next time you go below 20% Resolve, heal for 50% Resolve
Minor Boons	Gold Magnet	50% more Aureus coins found
Minor Boons	Gold Mine	Aureus coins found on this floor are doubled
Minor Boons	Gold Trophy	Your aureus coins are increased by 10% on room completion (removed when you purchase something from the Merchant)
Minor Boons	Hare Foot	60% increased Movement Speed
Minor Boons	Lilting Melody	Gain 400 Inspiration if you complete the next 2 rooms without losing Resolve or Inspiration
Minor Boons	Lilting Melody	Gain 400 Inspiration if you complete the next room without losing Resolve or Inspiration
Minor Boons	Lustrous Pearl	Traps are slower ^{editor's note: can have negative effects - slows down the fog in Lycia's hallway sequence}
Minor Boons	Mellifluous Chorus	40% less Resolve lost while you have Inspiration ^{editor's note: affects both Resolve and Inspiration loss}
Minor Boons	Mirror of Fortune	Duplicate a random Offer Reward ^{editor's note: only applies to rewards deferred to end of Floor/Sanctum; applies immediately once obtained to your current rewards}
Minor Boons	Ornate Dagger	You and your minions deal 50% more Damage
Minor Boons	Prayer Beads	Cannot lose Resolve until you complete the next room ^{editor's note: does not affect Inspiration loss}
Minor Boons	Rusted Chimes	Gain +100 Inspiration when you gain an Affliction
Minor Boons	Rusted Descry	50% increased Resolve recovered
Minor Boons	Sanguine Vial	Monsters have 30% less Maximum Life
Minor Boons	Scrying Crystal	You can see an additional room ahead on the Sanctum Map
Minor Boons	Silver Chalice	The next Minor Boon you gain is converted into a random Major Boon
Minor Boons	Silver Tongue	50% reduced Merchant prices ^{editor's note: stacks additively with Austerity Pact to make all Merchant items free}
Minor Boons	Tarnished Coin	100% increased Aureus coins gained while Resolve is below 50%
Minor Boons	Tarnished Descry	+200 to Maximum Resolve
Minor Boons	Untuned Lute	+250 to Inspiration
Minor Boons	Viscous Ichor	Monsters have 20% reduced Action Speed ^{editor's note: can affect bosses' arena effect/despawn time}
Minor Boons	Wooden Effigy	Monsters impact 25% less Resolve ^{editor's note: affects both Resolve and Inspiration loss}

Affliction

Above your inspiration bar, major afflictions are grouped in a symbol with a very thick and bright purple bordered boon symbol, while all minor afflictions are grouped in a plain purple bordered affliction symbol. Afflictions are shown when hovering according symbol.
Afflictions grant various downsides to your Sanctum run and can reduce or prevent Resolve recovery, spawn additional traps, buff monsters, affect your Aureus generation, or hide rooms or rewards on the Sanctum Map.

Affliction Type	Affliction Name	Description
Major Afflictions	Anomaly Attractor	Rooms spawn Volatile Anomalies
Major Afflictions	Chiselled Stone	Monsters Petrify on Hit ^{editor's note: free for Trickster/Juggernauts with minimum Action Speed}
Major Afflictions	Cutpurse	You cannot gain Aureus coins
Major Afflictions	Deadly Snare	Traps impact infinite Resolve ^{editor's note: some persistent skills from Sanctum monsters (e.g. Undying Archmage's floating balls' projectiles and explosion) count as traps and will end the run immediately on hit}
Major Afflictions	Death Toll	Lose 250 Resolve after completing 8 rooms ^{editor's note: this Resolve loss is considered similar to taking a hit, and will remove Inspiration before Resolve}
Major Afflictions	Demonic Skull	Cannot recover Resolve
Major Afflictions	Ghastly Scythe	Losing Resolve ends your Sanctum (removed after 3 rooms)
Major Afflictions	Ghastly Scythe	Losing Resolve ends your Sanctum (removed after 2 rooms)
Major Afflictions	Ghastly Scythe	Losing Resolve ends your Sanctum (removed after 1 room)
Major Afflictions	Glass Shard	The next Boon you gain is converted into a random Minor Affliction ^{editor's note: This Affliction's Boon to Affliction transformation can still occur with Unassuming Brick}
Major Afflictions	Orb of Negation	Non-Unique Relics have no Effect
Major Afflictions	Unassuming Brick	You cannot gain any more Boons ^{editor's note: Glass Shard's Boon to Affliction transformation can still occur with this Affliction}
Major Afflictions	Veiled Sight	Rooms are unknown on the Sanctum Map ^{editor's note: superseded by All-Seeing Eye}
Minor Afflictions	Accursed Prism	When you gain an Affliction, gain an additional random Minor Affliction
Minor Afflictions	Black Smoke	You can see one fewer room ahead on the Sanctum Map ^{editor's note: superseded by All-Seeing Eye}
Minor Afflictions	Blunt Sword	You and your Minions deal 25% less Damage
Minor Afflictions	Chains of Binding	Monsters inflict Binding Chains on Hit (Binding Chains: You are slowed by Binding Chains. Move to break the chains) ^{editor's note: 20% reduced Movement Speed per stack}
Minor Afflictions	Charred Coin	50% less Aureus coins found
Minor Afflictions	Concealed Anomaly	Guards release a Volatile Anomaly on Death
Minor Afflictions	Corrupted Lockpick	Chests in rooms explode when opened
Minor Afflictions	Dark Pit	Traps impact 100% increased Resolve ^{editor's note: affects both Resolve and Inspiration loss}
Minor Afflictions	Deceptive Mirror	You are not always taken to the room you select ^{editor's note: can randomly take player to a different connected room in the same column}
Minor Afflictions	Door Tax	Lose 30 Aureus coins on room completion
Minor Afflictions	Empty Trove	Chests no longer drop Aureus coins ^{editor's note: includes Reward Chests}
Minor Afflictions	Fiendish Wings	Monsters' Action Speed cannot be slowed below base Monsters have 30% increased Attack, Cast and Movement Speed
Minor Afflictions	Floor Tax	Lose all Aureus on floor completion
Minor Afflictions	Gargoyle Totem	Guards are accompanied by a Gargoyle
Minor Afflictions	Golden Smoke	Rewards are unknown on the Sanctum Map ^{editor's note: superseded by All-Seeing Eye}
Minor Afflictions	Haemorrhage	You cannot recover Resolve (removed after killing the next Floor Boss)
Minor Afflictions	Honed Claws	Monsters deal 25% more Damage
Minor Afflictions	Hungry Fangs	Monsters impact 25% more Resolve ^{editor's note: affects both Resolve and Inspiration loss}
Minor Afflictions	Liquid Cowardice	Lose 10 Resolve when you use a Flask ^{editor's note: removes Inspiration before Resolve; bricks a run with Ghastly Scythe; can also brick during Lycia's second form if flasks unless flasks are unequipped}
Minor Afflictions	Mark of Terror	Monsters inflict Resolve Weakness on Hit (Resolve Weakness: Hits against you impact 50% more Resolve) ^{editor's note: affects both Resolve and Inspiration loss}
Minor Afflictions	Phantom Illusion	Every room grants a random Minor Affliction (Afflictions granted this way are removed on room completion)
Minor Afflictions	Poisoned Water	Gain a random Minor Affliction when you use a Fountain
Minor Afflictions	Purple Smoke	Afflictions are unknown on the Sanctum Map ^{editor's note: superseded by All-Seeing Eye}
Minor Afflictions	Rapid Quicksand	Traps are faster ^{also affects Skull traps and Lycia's hallway fog}
Minor Afflictions	Red Smoke	Room types are unknown on the Sanctum Map ^{editor's note: superseded by All-Seeing Eye}
Minor Afflictions	Rusted Coin	The Merchant only offers one choice ^{supersedes additional option Relic modifiers}
Minor Afflictions	Rusted Mallet	Monsters always Knockback Monsters have increased Knockback Distance ^{editor's note: can cause issues during Lycia's Lightning Maze}
Minor Afflictions	Spiked Exit	Lose 5% of current Resolve on room completion ^{editor's note: ignores Inspiration. Bricks a run with Ghastly Scythe. Cannot reduce Resolve below 1}
Minor Afflictions	Spiked Shell	Monsters have 30% more Maximum Life
Minor Afflictions	Spilt Purse	Lose 20 Aureus coins when you lose Resolve from a Hit ^{editor's note: does not apply when losing Inspiration}
Minor Afflictions	Tattered Blindfold	90% reduced Light Radius Minimap is hidden
Minor Afflictions	Tight Choker	You can have a maximum of 5 Boons
Minor Afflictions	Unhallowed Amulet	The Merchant offers 50% fewer choices
Minor Afflictions	Unhallowed Ring	50% increased Merchant prices
Minor Afflictions	Unholy Urn	50% reduced Effect of your non-Unique Relics
Minor Afflictions	Unquenched Thirst	50% reduced Resolve recovered
Minor Afflictions	Voodoo Doll	100% more Resolve lost while Resolve is below 50% ^{editor's note: affects both Resolve and Inspiration loss}
Minor Afflictions	Weakened Flesh	-100 to Maximum Resolve ^{editor's note: cannot reduce Resolve below 1}
Minor Afflictions	Worn Sandals	40% reduced Movement Speed

Room Layouts

See the above link for annotated minimaps of each room type, including enemy locations and shortcuts. Each room other than the miniboss room contains several Guard unique monsters, as well as one of three tasks to complete the room:

Find the Exit (locate the exit door)
Defeat all the Guards (defeat every Unique Guard)
Defeat the Boss (minibosses based on map bosses)

Sanctum Layout
Room Goal	Defeat all the Guards	Defeat all the Guards (Skull Arena)	Find the Exit	Find the Exit (Traps)	Defeat the Boss (Miniboss)
Floor 1: Sanctum Archives	Chambers of Inscription	Templar Annals 1 central Skull, walls	Abandoned Library Ice Traps	Holy Trials Mana Rune Squares	Scriptorium Crimson Archbishop
Floor 2: Sanctum Vaults	Derelict Caverns	Battlegrounds 1 central Skull, no walls	Decrepit Cellar Ice Traps	Gauntlet Rolling Exarch Boulders	Reliquary Greater Wraith
Floor 3: Sanctum Cathedral	Unholy Lair	Infernum 2 Skulls, dividing wall	Halls of Worship Ice Traps	Crucible Mana Rune Squares and Skull	Sanctum Bellum Aureate Guardian
Floor 4: Sanctum Necropolis	Lost Catacombs	Desecrated Crypt 1 Skull, 90 degree arc	Undercroft Ice Traps and Skull	Entombment Rolling Exarch Boulders or Mana Rune Squares + Lasers	Mausoleum Colossal Lithomancer

Note: most "Find the Exit" rooms have shortcuts that require movement skills.

Room Reward Types

Note: All room types other than boss rooms can become Afflicted. Afflicted rooms are indicated by a purple border and cause the character to gain an Affliction on entry.

Item Reward Room

When players are offered rewards, they have three options:

Receive #x <item1> now
Receive #x <item2> at end of the Floor ("at end of the next Floor" if on room 8)
Receive #x <item3> on completing the Sanctum

The quantity and/or types of items improve based on the area level of the zone, the current floor, and how long you defer the reward, at the cost of risking the reward entirely if the player fails the run. Item chests have a 5 Aureus fee to open.

Rarer items like Divine OrbDivine OrbStack Size: 10Randomises the numeric values of the random modifiers on an itemRight click this item then left click a magic, rare or unique item to apply it.
Shift click to unstack., Exalted OrbExalted OrbStack Size: 10Augments a rare item with a new random modifierRight click this item then left click a rare item to apply it. Rare items can have up to six random modifiers.
Shift click to unstack., Sacred OrbSacred OrbStack Size: 10Randomises the numeric values of base defences on an armourRight click this item then left click an armour to apply it.
Shift click to unstack., Veiled Chaos OrbVeiled Chaos OrbStack Size: 10Reforges a rare item with new random modifiers, including a Veiled modifier. Can only be used on items that can have a Veiled modifier.Right click this item then left click a rare item to apply it.
Shift click to unstack. become available on Floor 3 and 4.

Treasure Reward Room

Contains chests of Aureus; comes in 2 types: Minor Treasure Reward (2 chests) or Major Treasure Reward (5 chests).

Fountain

Fountain rooms contain an interactable Fountain which grants Recover 25% of Maximum Resolve for a 5 Aureus fee.

Benevolent Fountain

Benevolent Fountain rooms contain an interactable Benevolent Fountain which grants Gain a Random Boon for a 150 Aureus fee.

Afflicted Fountain

Afflicted Fountain rooms contain an interactable Afflicted Fountain which grants Recover 50% of Maximum Resolve, but also inflicts a random minor Affliction on you, for a 5 Aureus fee.

Radiant Fountain

Radiant Fountain rooms contain an interactable Radiant Fountain which grants a random Boon, removes a random Affliction, and grants 200 Inspiration for a 5 Aureus fee. Rerolls Afflictions on Afflicted Rooms on the current floor if an Affliction was removed.

Merchant

Merchant rooms contain the NPC Sister Divinia who sells you Boons, Templar relics, or Sanctified Relics in exchange for Aureus. She can also recover 50 Resolve for a 200 Aureus fee. The Merchant is unlocked in Act 2 after completing the quest In Search of the Sanctum.

Accursed Pact

Accursed Pact rooms allow you to accept any of three random Accursed Pacts which grants both an upside and downside, as well as an item reward upon accepting at least 1 Accursed Pact. Accursed Pacts are unlocked in Act 7 after completing the quest Sanctum Temptations.

Accursed Pact outcomes
Icon	Upside	Downside
	Gain a specific Minor Boon	Lose 25% Maximum Resolve
	Gain a random Major Boon	Lose 50% Maximum Resolve
	Gain 2 random Minor Boons	Lose 50% Maximum Resolve
	Gain a specific Minor Boon	Gain a specific Minor Affliction
	Gain a specific Minor Boon	Gain a random Minor Affliction
	Gain a random Minor Boon	Gain a random Minor Affliction
	Gain 3 random Minor Boons	Gain a specific Major Affliction
	Lose a random Minor Affliction	Lose a random Minor Boon
	Remove a specific Minor Affliction	Gain a random Minor Affliction
	Lose 3 random Minor Afflictions	Gain a random Major Affliction
	Lose 3 random Minor Boons	Gain a random Major Boon
	Gain 200 Inspiration	Lose 200 Resolve
	All but 1 Maximum Resolve is converted to Inspiration	Maximum Resolve is 1
	Gain Aureus coins equal to the amount of Inspiration removed	Remove all Inspiration
	Gain 50% of current Resolve as Aureus coins	Lose 50% of current Resolve
Apex Pact	50% less Resolve lost in Boss Rooms	100% more Resolve lost in non-Boss Rooms
Austerity Pact	Merchant prices are reduced by 50%	Monsters do not drop Aureus coins
File:Pact Twin.png Doubling Pact	Guards are Twinned	Guards are Twinned
Indomitable Pact	Gain 30 Inspiration at the start of every room	Inspiration resets every room
Pyrrhic Pact	Resolve recovered is doubled	Maximum Resolve is lowered by 50% of recovered Resolve

The options that state "Lose #% Maximum Resolve" will not fail the run if Maximum Resolve is 1.

Attempting to use the Gain 200 Inspiration, Lose 200 Resolve Pact when you have less than 200 Resolve will cause an error, stating "Not enough Resolve".

Boss Room

Always the 8th room of any floor.

Bosses

Minibosses

Sanctum Minibosses
Boss name	Boss room name	Based on:
Crimson Archbishop	Sanctum Archives: Scriptorium	Kadaris, Crimson Mayor; cannot be hurt directly - defeat all the Crimson Priest clones while avoiding his spells. The spells' coverage increases as more clones are defeated.
Greater Wraith	Sanctum Vaults: Reliquary	The Restless Shade; creates several rows of coffins and uses SoulrendSoulrendChaos, Spell, AoE, Duration, Projectile Level: (1-20) Cost: (14-26) Mana Cast Time: 0.80 sec Critical Strike Chance: 5.00% Effectiveness of Added Damage: 170%Requires Level 28Fires a projectile that turns towards enemies in front of it, damaging and piercing through those it hits, and leeching some of that damage as energy shield. As the projectile travels, it repeatedly applies a short but powerful chaos damage over time debuff to each enemy in an area around it.Deals (21-885) to (31-1327) Chaos Damage Projectiles Pierce all Targets Deals (180.8-2642.5) Base Chaos Damage per second Base duration is 0.6 seconds Modifiers to Spell Damage apply to this Skill's Damage Over Time effect 4% of Spell Damage Leeched as Energy Shield Additional Effects per 1% Quality: 1% increased Chaos DamagePlace into an item socket of the right colour to gain this skill. Right click to remove from a socket.
Aureate Guardian	Sanctum Cathedral: Sanctum Bellum	The Purifier; uses Divine Flare and rune slams.
Colossal Lithomancer	Sanctum Necropolis: Mausoleum	High Lithomancer; can create a small ring or cover a quarter or the entire arena in floating rocks that explode in an area after a delay.

Floor Bosses

Sanctum Bosses
Boss Name	Boss Room	Description
Varakath, the Waxen	Sanctum Archives: Candlelit Chapel	Based on Candlemass (POE2); also uses Blazing SalvoBlazing SalvoSpell, AoE, Fire, Projectile Level: (1-20) Cost: (8-23) Mana Cast Time: 0.70 sec Critical Strike Chance: 6.00% Effectiveness of Added Damage: 60%Requires Level 12Fires projectiles which fly in an arc, exploding on impact with either enemies or the ground near where you target. Targeting farther away causes the projectiles to spread out and land over a wider area.Deals (7-270) to (10-405) Fire Damage Fires (4-6) additional Projectiles Additional Effects per 1% Quality: 0.5% increased Area of EffectPlace into an item socket of the right colour to gain this skill. Right click to remove from a socket. and a fire breath attack
Braom, the First Experiment Uzar, the Second Experiment	Sanctum Vaults: Experimentation Chamber	Slow moving statues that use slams. Changes size based on the other's lost health. Both bosses enrage and heal to full when the other dies. Enraged Braom can use a multidirectional Glacial Cascade (similar to the Delirium modifier Burrowing Blade), or repeated Sunders while walking. Enraged Uzar can also create a homing Blood Orb leaving Enervating Ground, or use a Ground Slam that fires random projectiles.
Xenathar, Templar Reaper	Sanctum Cathedral: Hall of Mirrors	Base on Vorana, Last to Fall; also uses wall-bouncing lasers, Divine Flare, and slow-moving Innocence projectile nova.
Lycia, Unholy Heretic	Sanctum Necropolis: Sanctum Sanctorum	Form 1: Attacks with sword swings and lunges, circular sweep attacks, and a rotating red beam. Can summon Igneous Gargoyle adds and spawns a ring of DOT ground effect that drains Resolve and slowly moves through the arena.
Lycia, Herald of the Scourge	The Beyond	Form 2: Uses a wind tunnel beam, returning FireballFireballProjectile, Spell, AoE, Fire Level: (1-20) Cost: (6-25) Mana Cast Time: 0.75 sec Critical Strike Chance: 6.00% Effectiveness of Added Damage: 370% Projectile Speed: 1040 AoE Radius: 9Unleashes a ball of fire towards a target which explodes, damaging nearby foes.Deals (9-1640) to (14-2460) Fire Damage 25% chance to Ignite enemies Projectiles gain Radius as they travel farther, up to +(0-9) Radius Additional Effects per 1% Quality: 1% increased Projectile SpeedPlace into an item socket of the right colour to gain this skill. Right click to remove from a socket.s, and a delayed slam; also summons spinning staff hazards around the arena. Periodically has an immune phase creating a maze of waves of lightning bolts with gaps. Note: This phase does not damage Resolve.

Minibosses and bosses drop a large quantity of Aureus and have a chance to drop Templar relics (or Sanctified Relics at area levels >75).
Killing each miniboss and boss for the first time unlocks several tiles in the Relic Altar.
Boss rooms contain a chest for any accumulated Item Rewards for the floor, as well as two additional Item Reward chests.

Lycia

After defeating Lycia's first form, the player can either directly exit to the reward chest via the staircase (and therefore unable to enter The Beyond), or enter The Beyond to challenge her second phase. Dying during the second phase will end the run and prevent looting of the reward chest.
Lycia's second form is only encounterable in an area of level 80 (T13+ maps); she will only taunt the player after being killed in lower areas.
Lycia's second form does not interact with Resolve mechanics; however, it is still possible to fail from the Resolve mechanic if the player has an Affliction that removes Resolve on Flask use.

Lycia, Herald of the Scourge in "The Beyond" will always drop a Sanctified Relic, as well as 1 of:

Sandstorm VisageSandstorm Visage
Necromancer CircletEnergy Shield: (165-224)Requires Level 54, 112 Int(8-10)% increased Cast Speed
(200-250)% increased Energy Shield
Avoid interruption from Stuns while Casting
Base Spell Critical Strike Chance is equal to that of Main Hand Weapon
Cannot deal Critical Strikes with AttacksA fell wind brings death.
The Balance of TerrorThe Balance of Terror
Cobalt JewelLimited to: 1+(10-15)% to all Elemental Resistances
<2-3 random curse modifiers>Fellshrine stood as a holy bastion opposite the
Chamber of Sins, and all that it represented.
For one to rise, the other must fall.Place into an allocated Jewel Socket on the Passive Skill Tree. Right click to remove from the Socket.
Eternal DamnationEternal Damnation
Agate AmuletRequires Level 52+(16-24) to Strength and Intelligence+(40-70) to maximum Mana
+(-13-13)% to Chaos Resistance
-5% to all maximum Resistances
Gain additional Elemental Damage Reduction equal to half your Chaos ResistanceThe price of immortality is isolation.
The Winds of FateThe Winds of Fate
Foul StaffWarstaff
Physical Damage: (520-585) to (968-1089)
Critical Strike Chance: 6.10%
Attacks per Second: 1.30
Weapon Range: 13Requires Level 55, 94 Str, 94 Int+18% Chance to Block Attack Damage while wielding a Staff(700-800)% increased Physical Damage
+100% to Global Critical Strike Multiplier
75% of Physical Damage converted to a random Element
25% of Physical Damage Converted to Chaos Damage
Maximum Critical Strike Chance is 50%
Non-Critical Strikes deal no DamageLife... Death...
The whim of the cosmos.

Additionally, Lycia's second form also drops a random Unique Relic, which are one-time use Relics that provide additional challenge and rewards to a Sanctum run in areas of level 80+. She is also required to be killed to drop Original SinOriginal Sin
Amethyst RingRequires Level 52+(17-23)% to Chaos ResistanceAll Elemental Damage Converted to Chaos Damage
Nearby Enemies' Chaos Resistance is 0Innocence rose to godhood not on inspired faith,
but on the vilification and hatred of another. or Invocations used to corrupt and add Keystones to Sanctified Relics by completing the aforementioned Unique Relic challenges.

Relic Altar

The Relic Altar is unlocked in Act 2 after completing the quest In Search of the Sanctum.
Each character has its own Relic Altar and uses separate Relics. However, the Relic Locker is shared between all of your characters in the same league.^[2]
Relics placed in the Relic Altar are locked in for the entire Sanctum run as soon as they are confirmed and cannot be added or removed in the middle of a run. The current run must be completed, failed, or forfeited to add or remove Relics.^[2]
The Relic Altar contains 18 inventory spaces, but 12 are initially locked.

The Relic Altar in its initial state
Fully unlocked Relic Altar

Unlocking

Locked inventory spaces for the Relic Altar can be unlocked by completing various rooms or floors in the Forbidden Sanctum.

Row	Column	Unlocking Requirement
1	1	Complete the Sanctum Bellum room in the Sanctum Cathedral
1	2	Complete the Sanctum Archives
1	3	Complete the Sanctum Archives
1	4	Complete the Sanctum Vaults
2	1	Complete the Sanctum Vaults
2	5	Complete the Sanctum Cathedral
3	1	Complete the Sanctum Cathedral
3	5	Complete the Sanctum Necropolis
4	2	Complete the Sanctum Necropolis
4	3	Complete the Scriptorium room in the Sanctum Archives
4	4	Complete the Reliquary room in the Sanctum Vaults
4	5	Complete the Mausoleum room in the Sanctum Necropolis

Templar Relic

Templar Relics are a type of item that is exclusive to the Sanctum league. They can be placed in the Relic Altar to provide buffs to various mechanics related to the Forbidden Sanctum.

Templar Relics can be found in the Sanctum as rewards from guards, minibosses or bosses, or purchased from Sister Divinia for 300 Aureus.
They can be stored in a special separate stash, which can also be placed as a hideout decoration.
To equip a Relic, they must be placed in the Relic Altar on a 5x4 grid with some slots blocked off. Additional grid slots can be unlocked as you progress, up to a total of 18 slots.
Relics are unmodifiable and account-bound, and are always Magic.
Templar Relics can be vendored 5 to 1 to obtain a new one with random modifiers.

Item	Drop Level
Censer Relic Censer RelicUnmodifiablePlace this item on the Relic Altar at the start of each Sanctum runAccount-bound	1
Urn Relic Urn RelicUnmodifiablePlace this item on the Relic Altar at the start of each Sanctum runAccount-bound	1
Coffer Relic Coffer RelicUnmodifiablePlace this item on the Relic Altar at the start of each Sanctum runAccount-bound	45
Processional Relic Processional RelicUnmodifiablePlace this item on the Relic Altar at the start of each Sanctum runAccount-bound	60
Tome Relic Tome RelicUnmodifiablePlace this item on the Relic Altar at the start of each Sanctum runAccount-bound	60
Candlestick Relic Candlestick RelicUnmodifiablePlace this item on the Relic Altar at the start of each Sanctum runAccount-bound	75
Papyrus Relic Papyrus RelicUnmodifiablePlace this item on the Relic Altar at the start of each Sanctum runAccount-bound	75

Sanctified Relic

Sanctified Relics are a type of item that is exclusive to the Sanctum league. Sanctified Relics are special versions of Templar relics that provide more general modifiers to the character, and have effect even outside of the Forbidden Sanctum^[3]. They are marked with an orange glow behind the item's art. They can be placed in the Relic Altar to provide stats to the character directly both inside and outside the Sanctum.

Sanctified Relics can be found in the Sanctum as rewards from guards, minibosses or bosses, or purchased from Sister Divinia for 600 Aureus in areas of level 75 or higher.
They can be stored in a special separate stash, which can also be placed as a hideout decoration.
Sanctified Relics are equipped in the inventory separately from the Templar relics in the Relic Altar, and limited to 1. They are not considered an equipped item, similar to Thief's TrinketThief's TrinketCorruptedYou must find the sculpture The Catch in a Smuggler's Den or Underbelly Blueprint to be able to equip this.
Relics are unmodifiable and account-bound, and are always Magic.
Sanctified Relics can be vendored 5 to 1 to obtain a new one with random modifiers.
Sanctified Relics can be corrupted by using an invocation, which adds a fixed Keystone as a corrupted implicit modifier.

Item	Drop Level		Additional Drop Restrictions
Sanctified Relic Sanctified RelicLimited to: 1Requires Level 60Place this item on the Relic Altar to affect your character	75	60	Can be found in the Forbidden Sanctum as rewards from minibosses or bosses, or purchased from Sister Divinia for Aureus.
Sanctified Relic Sanctified RelicLimited to: 1Requires Level 60Place this item on the Relic Altar to affect your character	75	60	Can be found in the Forbidden Sanctum as rewards from minibosses or bosses, or purchased from Sister Divinia for Aureus.
Sanctified Relic Sanctified RelicLimited to: 1Requires Level 60Place this item on the Relic Altar to affect your character	75	60	Can be found in the Forbidden Sanctum as rewards from minibosses or bosses, or purchased from Sister Divinia for Aureus.

Party mechanics

The Sanctum's choices are made by the map's instance owner.
All party members share the Resolve bar.

Ruthless mode

In Ruthless mode, Item Rewards do not offer immediate rewards, and instead only offer either end-of-floor rewards or end-of-Sanctum rewards.

Version history

Version	Changes
3.20.2	Some Sanctum monsters can now be Spectred, and Spectred versions of Stalking Geist will now be able to attack enemies. Lowered the resistances and maximum attack distance of the Spectred version of Igneous Gargoyle.
3.20.1b	The Death Toll Major Affliction no longer causes monsters to drop no Aureus Coins. Instead, it now causes you to Lose 250 Resolve after completing 8 rooms. This change does not affect existing Sanctum runs. Herald of the Scourge's lightning waves skill now spawns more lightning bolts with each wave, though the lightning bolts are now smaller. The delay between each wave has been slightly increased, and the damage of the skill has been lowered by 20%. Improved the visibility of the ground degen effect when fighting Lycia, Unholy Heretic. Added an error message for attempting to change your Relics while you have an active Sanctum.
3.20.1	Introduced 7 new Unique Relics that drop from the final form of the Sanctum Boss. These Relics challenge you to complete an entire run of The Forbidden Sanctum at area level 80+ under special rules. If you're able to complete such a run, you'll be rewarded in new and special ways. However, the Unique Relic will be destroyed regardless of the outcome of your run, so if you fail to complete it, you'll forfeit your potential rewards. Some of these Unique Relics cause the Herald of the Scourge to drop additional or specific items, while others causes Aureus Coins to be converted to certain outcomes upon defeating the Herald of the Scourge. We've also introduced a new Unique RingOriginal Sin Amethyst RingRequires Level 52+(17-23)% to Chaos ResistanceAll Elemental Damage Converted to Chaos Damage Nearby Enemies' Chaos Resistance is 0Innocence rose to godhood not on inspired faith, but on the vilification and hatred of another. that can be earned by defeating the Herald of the Scourge with one of the new Unique RelicsThe Original Scripture Papyrus RelicRequires Level 64The Herald of the Scourge drops the Original Sin Cannot have Inspiration Maximum Resolve is 1 This item is destroyed when your Sanctum endsUnmodifiable"It's all here. The lie at the core of my faith. Maxarius was not the first chosen of Innocence. Maxarius was Innocence himself. A charlatan, a liar, and a power-seeker." - Lycia, the HereticPlace this item on the Relic Altar at the start of each Sanctum runAccount-bound active. Introduced 41 new "Lycia's Invocation" currency items. These can be applied to non-Corrupted Sanctified Relics to add their respective Keystone to the Relic. Boons and Afflictions that provide increases and reductions to the effect of your Relics now specify that they do not affect Unique Relics. Characters that are up close to their target now take even less damage to their Resolve. Sanctum Quests are no longer hidden with the "Enable Quest Tracking" option disabled. We've also made improvements to these Quests to reduce the chance they are missed when first entering the relevant town area. Party Members are now able to view the Map of the area owner's Sanctum, if they currently have a run active. Party members can now store a Sanctum room for later when the map owner runs their Sanctum room for the area. The Resolve bar now flashes when you heal or damage your Resolve. Added a display to show which Affliction was removed when you cleansed an Affliction. The Sanctified Relic Slot has been moved from the Sanctum Map and is now located in the Inventory panel. Sanctified Relics can now be compared with your equipped one by using the Compare Item Descriptions keybind (Ctrl, by default). The wave skill used by the final form of the Sanctum Boss now spawns far fewer lightning bolts with each wave, though the lightning bolts are slightly larger. The delay between each wave has also been slightly increased. You can no longer gain a new multi-stage Boon or Affliction, such as Lilting Melody, if you already have a later stage of that same Boon or Affliction. The Hungry Fangs Affliction and Wooden Effigy Boon now impact Resolve multiplicatively, instead of being additive with stats that impact resolve on Relics. Tweaked the position of the skulls that fire tracking beams in the third floor of the Sanctum. Updated the Prayer Beads Boon to clarify Resolve is able to be lost after the next room has been completed.
3.20.0b	Gaining increases to your maximum Resolve now heals your Resolve by that same amount. Relics are now able to be dropped onto the ground by players, though these still remain Account-bound to the player that dropped them. The pickup range of Aureus Coins has been increased, and you're now able to pick them up slightly sooner after they drop. Reduced the damage dealt to minions for some of the skills used by the Sanctum end boss in their true form. Infernal Sentinel Sanctum Guard's Cleave attack now fires three times fewer projectiles. Improved the warning text that is displayed when you try to enter the final reward room in Sanctum.
3.20.0	Introduced to the game. There's now a Relic Locker in the Sanctum subarea where you pick what room to do next.

References

↑ https://twitter.com/pathofexile/status/1598434028398706688
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Community_Team (December 04, 2022). "Recently Asked Questions". Official Path of Exile Forums. Retrieved December 05, 2022.
↑ https://www.pathofexile.com/forum/view-thread/3324396

[1] ttps://twitter.com/pathofexile/status/1598434028398706688

[RAQ-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Community_Team (December 04, 2022). "Recently Asked Questions". Official Path of Exile Forums. Retrieved December 05, 2022.

[3] ttps://www.pathofexile.com/forum/view-thread/3324396

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[2]

[3]