Progenesis

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Progenesis
Amethyst Flask
Lasts 7.41 Seconds
Consumes 29 of 65 Charges on use
+35% to Chaos Resistance
Requires Level 18(17)% reduced Charges per use
(14)% increased Duration
When Hit during effect, 25% of Life loss from Damage taken occurs over 4 seconds instead
They were bred in a cosmic ocean of raw creation.
Feasting and drinking of the milk of the mother,
they fought to the death for every last drop.
Right click to drink. Can only hold charges while in belt. Refills as you kill monsters.
Acquisition
Drop restricted
Drops from Uber Uber Elder.
Vendor Offer
1x Scroll Fragment
Metadata
Item class: Utility Flask
Progenesis
Flask Effect

Progenesis is a unique Amethyst FlaskAmethyst FlaskLasts 6.50 Seconds
Consumes 35 of 65 Charges on use
+35% to Chaos Resistance
Requires Level 18Right click to drink. Can only hold charges while in belt. Refills as you kill monsters.
.

Modifiers

Item acquisition

Progenesis has restrictions on where or how it can drop. It cannot be chanced.

Drops from Uber Maven.

Ruthless mode

Utility Flasks cannot gain charges while active in Ruthless mode. This flask also has a flask duration of ~5.13 seconds instead.

Design attribution

Progenesis was created in a collaboration with Ben as a reward for taking a prize place in the 3.18 boss kill event.[1]

Version history

Version Changes
3.20.0
  • Introduced to the game.

References

  1. Community_Team (May 23, 2022). "Sentinel Boss Kill Event Announcement". Official Path of Exile Forums. Retrieved August 8, 2022.